An introductory course covering basic principles of quantitative analysis of biological samples based on classical volumetric techniques and modern instrumental methods including spectroscopy and chromatography.

Students will be introduced to the standard tools and techniques employed in Chemical Biology research.

A survey of thermodynamic and kinetic principles and their application to biological and environmental systems.

Systematically investigate issues in Chemical Biology while developing skills in formulating and refining questions, searching and analyzing the scientific literature, and written and oral presentation.

A research project will be formulated and addressed using the tools of Chemical Biology.

Chemistry and biology of primary metabolism. Synthesis, biosynthesis and degradation of carbohydrates, nucleotides, and proteins are compared and contrasted by studying reaction mechanisms and catalysis.

Applications of spectroscopy detailing the use of NMR, MS, IR, and UV in determining structures of small molecules and biomolecules with a particular focus on natural products.

Principles of interactions between macromolecules (proteins, nucleic acids), and macromolecules with small ligands. Techniques for characterizing and quantifying biomolecular interactions in vitro and in vivo.

Advanced separation and detection principles for high-throughput bio-assays for drug targets, as well as recent global analytical strategies for genomic, proteomic and metabolomic analyses.

A project supervised by a member or associate member of the Department of Chemistry and Chemical Biology involved in the Chemical Biology program.

A thesis based on a major research project supervised by a member or associate member of the Department of Chemistry and Chemical Biology involved in the Chemical Biology program.

Inorganic elements and their behaviour in biological systems. Topics for study include metalloenzymes, bio-redox agents, transport proteins, biomimetic inorganic complexes, metallodrugs, and radiopharmaceuticals.

A description of basic building blocks and reaction mechanisms involved in the biosynthesis of naturally occurring compounds.

Topics will include lead compound discovery strategies; high-throughput screening and "in silico" screening; exploration of structure-activity relationships; drug targets and molecular mechanisms of drug action; strategies for drug optimization.

A discussion of organic chemistry, chemical kinetics, acid-base equilibrium, and the energetics of phase transformations, with emphasis on relevant experimental techniques and solving real problems ranging from drug discovery to environmental chemistry.

An introduction to chemical principles for Engineering students, including reactivity, bonding, structure, energetics and electrochemistry.

A general introduction to chemistry, suitable for students without Grade 12 Chemistry U.

An introduction to the basic principles of analytical chemistry, with particular emphasis on solution equilibria and classical methods of analysis.

The art and science of performing quantitative analysis on samples based on classical volumetric techniques and modern instrumental methods including electrochemistry, optical spectroscopy, and chromatography.

An introduction to the chemistry of monofunctional aliphatic compounds with emphasis on reactions and their mechanisms. Special topics will include synthetic and natural polymers.

The basic theories and models of bonding and structure that explain the combination of elements across the periodic table with primary emphasis on the main-group elements.

Selected experiments that introduce and develop the basic techniques and skills associated with the synthesis of organic and inorganic molecules; characterization and analysis of molecules, materials, and solutions.

Advanced techniques for synthesis and characterization of organic and inorganic molecules and materials, and the use of modern instrumentation in chemistry.

An introduction to organic chemistry with emphasis on the reactions of functional groups and an introduction to spectroscopic techniques for structure determination.

Nucleophilic substitutions at carbonyl centres, aromatic chemistry, carbohydrates, applications of spectroscopic techniques in organic chemistry.

Examines how structure affects properties and chemistry of organic molecules important for life, health, and advanced technologies. Fundamentals of organic reaction mechanisms and structure determination.

Survey of fundamental reactions used to construct organic molecules, with emphasis on reaction mechanisms. Introduction to functional group interconversions, and construction of complex organic molecules.

An introduction to vector calculus, differential equations and linear algebra - including solving linear equations, eigenvalues and eigenvectors - motivated by problems of chemical equilibrium and kinetics.

Thermodynamics and its application to physical transformations and equilibria. Microscopic and macroscopic aspects of chemical kinetics.

An introduction to the tools of inquiry and their use in the investigation of modern issues of chemical and societal importance, with emphasis on central applications of chemistry and the role chemistry plays in addressing problems of societal relevance.

An introduction to inorganic chemistry. Emphasis on bonding and structure in inorganic compounds of representative main group and transition elements.

A systematic study of modern processes in the chemical, petrochemical and polymer industries, as well as their environmental impact and the role of emerging green chemistry technologies.

Advanced experimental inquiry projects in molecular science and advanced materials.

A survey of contemporary organic synthesis, including functional group manipulations, use of protecting groups, and strategic carbon-carbon bond forming reactions. Applications involving multistep syntheses of complex organic molecules will be presented.

An introduction to quantum chemistry and its applications in spectroscopy and structure and unusual phenomena at the nanoscale.

Microscopic origins of macroscopic properties with applications to nanomaterials, optical and magnetic materials, and green chemistry.

A 12-16 week research project undertaken in a chemistry laboratory during the summer following completion of Level III of an Honours Chemistry program, requiring the submission of a formal report. Students are responsible for arranging a suitable project, location, and agreement of the supervisor and the Department by May 1st.

Registration in the course will be in Term 1 of the Fall/Winter session immediately following the project.

Recent advances in analytical chemistry will include an introduction to chemometrics and multivariate analysis, as well as new developments in separation science and mass spectrometry.

A thesis based on a research project under the direction of a faculty member of the Department of Chemistry and Chemical Biology.

Structural methods such as multi-NMR, NQR, EPR, Mössbauer and vibrational spectroscopy are covered. Inquiry directed problems and topics illustrate applications in contemporary inorganic chemistry.

Inorganic elements and their behaviour in biological systems. Topics for study include metalloenzymes, bio-redox agents, transport proteins, biomimetic inorganic complexes, metallodrugs, and radiopharmaceuticals.

Structure-property relationships that form the basis for the technological applications of non molecular inorganic solids, including oxides, metals and intermetallic compounds.

Organometallic complexes and their reactivity, with a view towards catalyst design. An inquiry project is included.

A description of basic building blocks and reaction mechanisms involved in the biosynthesis of naturally occurring compounds.

Fundamental and modern polymerization methods, industrially and biomedically relevant polymers and their uses, will be covered. Emphasis will be placed on structure-property relationships.